Neglected Tropical Diseases

Likely hot spots include the Sahel, Ethiopian Highlands, Rift Valley, India, eastern China, Indonesia, and the Philippines. Climate change will drive animals towards cooler areas where their first encounters with other species will vastly increase the risk of new viruses infecting humans, researchers warned on Thursday. There are currently at least 10,000 viruses "circulating silently" among wild mammals that have the capacity to cross over into humans, mostly in the depths of tropical forests. As rising temperatures force those mammals to abandon their native habitats, they will meet other species for the first time, creating at least 15,000 new instances of viruses jumping between animals by 2070, according to a study published in the journal Nature. "We have demonstrated a novel and potentially devastating mechanism for disease emergence that could threaten the health of animal populations in the future, which will most likely have ramifications for our health t...

Today's early morning highlights from the major news organizations. KHN: Advance Care Planning For Guns: Owners Can Help Ensure Safe Use And Transfer Of Weapons Kerri Raissian didn't know what to do about her father's guns when he died of covid-19 in December at age 86 and left her executor of his estate. Her father, Max McGaughey, hadn't left a complete list of his firearms and where they were stored, and he hadn't prepared a realistic plan for responsibly transferring them to family members. (Graham, 4/27) KHN: Call It 'Mexicare': Fed Up With High Medical Bills, A Family Crosses The Border For Health Care The Fierro family of Yuma, Arizona, had a string of bad medical luck that started in December 2020. That's when Jesús Fierro Sr. was admitted to the hospital with a serious covid-19 ...

Hand-foot-and-mouth disease (HFMD) is a viral infection frequently encountered in the pediatric age group. Common culprits in such manifestations are coxsackievirus A16 and human enterovirus 71. The patient presents febrile with erythematous papulovesicular exanthems in the mouth, palms, and soles. HFMD is self-limiting in nature with a rare-complication rate. Onychomadesis is proximal nail separation while Beau's lines are whitish transverse lines and considered a rare complication of HFMD. Both allude to halted nail-matrix proliferation, and the pathophysiology behind such manifestations is still not yet understood. It is hypothesized that the virus elicits an inflammatory process, inhibiting nail-matrix proliferation or immune-complexes depositing on nails creating an embolism. Onychomadesis and Beau's lines appear after four to eight weeks of HFMD disease resolution and persist for approximately 35 days. There are no serious sequelae of those manifestations, as t...

Researchers at University of California San Diego School of Medicine and Jacobs School of Engineering, with colleagues at Baylor College of Medicine, have used a systems biology approach to parse the genetic diversity of C lostridioides difficile , a particularly problematic pathogen in health care settings. The Centers for Disease Control estimates that the bacterium causes approximately 500,000 infections in the United States annually, with severe diarrhea and colitis (inflammation of the colon) as characteristic symptoms. The researchers' findings are published in the April 27, 2022 online issue of PNAS . C. difficile is the most dominant cause of hospital-associated infections, in part from the use of antibiotics, which can kill enough healthy bacteria to allow C. difficile to grow unchecked. Infections are particularly dangerous in older persons. One in 11 people over the age of 65 who are diagnosed with a hospital-associated case of C. difficile die within one month, ...

[unable to retrieve full-text content] Area roundup: Hamilton's 4 event wins help Pullman boys take GSL dual meet    Moscow-Pullman Daily News

Roseola infantum is an infection caused by a type of herpes virus. It typically affects babies and toddlers. Other names for this health issue are sixth disease, exanthema subitum, or just "roseola." Around 90% of roseola cases occur before 2 years of age. This article summarizes how to identify roseola and how to tell the difference between this illness and measles. It also examines whether treatment is necessary. Roseola usually affects toddlers and babies under 2 years old . They may also have or show: general discomfort irritability an unwillingness to eat diarrhea a cough swelling or redness around the eyes ear pain swollen glands Roseola has a distinctive progression : A high fever develops, possibly suddenly, and may last for 3–5 days. A distinctive rash appears, usually on the torso, as the fever ends. The rash may progress to the neck, face, and limbs within 12–24 hours. The rash disappears after 1–2 days. The roseola rash may look like small pink spots or bumps tha...

Cook JK, Jackwood M, Jones RC. The long view: 40 years of infectious bronchitis research. Avian Pathol. 2012;41(3):239–50. Article  Google Scholar  Zhang X, Liao K, Chen S, Yan K, Du X, Zhang C, et al. Evaluation of the reproductive system development and egg-laying performance of hens infected with TW I-type infectious bronchitis virus. Vet Res. 2020;51(1):95. CAS  Article  Google Scholar  Chhabra R, Chantrey J, Ganapathy K. Immune responses to virulent and vaccine strains of infectious bronchitis viruses in chickens. Viral Immunol. 2015;28(9):478–88. CAS  Article  Google Scholar  Liu S, Kong X. A new genotype of nephropathogenic infectious bronchitis virus circulating in vaccinated and non-vaccinated flocks in China. Avian Pathol. 2004;33(3):321–7. CAS  Articl...

Moraxella catarrhalis (M. catarrhalis), also known as Branhamella catarrhalis (B. catarrhalis), is a type of bacteria that causes upper respiratory (nose, sinuses, and throat) and lower respiratory (lungs, bronchi, and bronchioles) infections. M. catarrhalis is typically found in the nasopharynx of young children and is one cause of childhood infections such as otitis media (middle ear infection), sinusitis (inflammation of the sinuses), and conjunctivitis (pink eye). Marco VDM / Getty Images It can also cause respiratory disease in adults, such as bronchopneumonia. In older people with chronic obstructive pulmonary disorder (COPD) (a long-term, inflammatory lung disease that blocks airflow to the lungs) or chronic bronchitis, it causes lower respiratory tract infections. Although rare, systemic (widespread) infections may occur, including infective endocarditis and meningitis. First reported in 1896, M. catarrhalis was originally named Micrococcu...