Neglected Tropical Diseases

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In December 2019, the China Health Authority notified the World Health Organization (WHO) of cases of pneumonia with an unknown etiology in Wuhan, China. They identified the virus as a novel coronavirus, initially called 2019-nCOV. However, further research revealed that it was associated with the 2002 SARS-CoV-1 outbreak, and the virus was re-named SARS-CoV-2 by the International Committee for Taxonomy of Viruses [1,2]. On March 11, 2020, WHO declared SARS-CoV-2 infection a pandemic due to its rapid spread and increased mortality rate worldwide [3]. SARS-CoV-2 is a single-stranded RNA virus that causes the disease known as coronavirus disease 2019 (COVID-19) in humans. The condition is not limited to the respiratory system; studies have shown the manifestations of the infection seen in other body systems, including but not limited to the hematologic, gastrointestinal, and cardiovascular systems [4-6]. Research has linked the virus to major cardiovascular...

Load-shedding causes chaos for 18-year-old girl who has to rush to hospital when electric-powered device stops working Premium By Asanda Nini - 29 September 2022 While persistent load-shedding cripples the economy, when it hits Mdantsane's NU13, it becomes a life-threatening situation for one teenage girl...

Your child is cranky, running a fever and going through tissues like there's no tomorrow.   Advertising Policy Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy Then, they won't eat.   Then, you see a rash. And their best friend's mom from daycare calls and says her child hasn't been feeling well either.  And now it's all making sense.  It might be hand, foot and mouth disease, a common but highly contagious childhood illness that makes its way — very quickly — through households, daycares and schools.   "Like most viruses, hand, foot and mouth is fairly contagious," says pediatrician Dana Schmidt, MD. "So, in a daycare or school setting, it can spread very quickly....

NEW YORK – The developers of the MasSpec Pen surgical device have demonstrated its usefulness for identifying microbes, broadening its potential applications beyond cancer. In a study published this month in Clinical Chemistry , a team led by Livia Eberlin, associate professor of surgery at Baylor College of Medicine and inventor of the MasSpec Pen, used the device to identify bacteria in cultured samples and Gram stain types and genus directly from clinical samples. Their findings raise the possibility that the pen could prove useful for quickly identifying bacteria during surgery for conditions like bone infection or diabetic foot infections, Eberlin said. The MasSpec Pen consists of a handheld, disposable ionization device connected to a mass spectrometer. It works via ambient ionization, using drops of water to extract lipids and metabolites from tissue that are then analyzed via mass spectrometry to generate molecular profiles. These can be used to distinguish between dif...

Trial supports protocol for reducing antibiotics in suspected sepsis cases An opt-out protocol for antibiotic de-escalation in patients with suspected sepsis resulted in more antibiotic discontinuations and less exposure to broad-spectrum antibiotics, with no evidence of harm, according to the results of a randomized controlled trial published today in Clinical Infectious Diseases. The trial, conducted in 10 US acute care hospitals from September 2018 through May 2020, aimed to quantify the effect of an antibiotic opt-out program targeting low-risk patients in whom systemic infection was not confirmed or who recovered quickly and were therefore candidates for antibiotic de-escalation. Eligible patients were randomly assigned to the opt-out protocol versus usual care. In the intervention arm, the clinician responsible for antibiotic treatment was encouraged to stop antibiotics based on an initial safety screen that determined the patient was not likely to have sepsis. If the clinician d...

There's no age requirement for excellence. You might have heard the aphorism "Youth is wasted on the young," but it's generally credited to Irish playwright George Bernard Shaw, a famously bitter curmudgeon—and besides, counterexamples can be found all around us. Take a good look at the Southwest Florida workforce and you'll see every profession being elevated and energized through the dedication and drive of younger generations. We're pleased to celebrate their efforts by presenting the Gulfshore Business 40 Under 40 for 2022. Inside you'll see representatives of dozens of industries from law to dentistry, real estate to public education, speech therapy to photography. And while their efforts at those vocations are undeniably impressive, inclusion in this list requires more than professional excellence and comparative youth; each honoree has also dedicated extra energy, time and talent to making his or her community a little better through philanthropi...

Sore throat is a common COVID-19 symptom, but it can also be from the flu, allergies, or a cold.  The best way to determine whether a sore throat is a symptom of COVID-19 is to take a test.  Medical experts also share other diagnostic and treatment tips for a sore throat. Up to 80% of sore throat cases happen due to viral infections, such as influenza, rhinovirus, and coronavirus.  COVID-19, another viral infection, can also cause a sore throat — but it may feel a little different. You may feel less soreness in your throat and more scratchiness, says Dr. Cassandra Pierre, an infectious disease physician at Boston Medical Center. Almost half of people with COVID-19 develop a sore throat, according to health data from the Zoe Health Study. The best way to be sure a sore throat isn't COVID-19 is to take a test, s...