Hit-To-Lead In-Depth Focus 2019 - Drug Target Review

Hit-To-Lead In-Depth Focus 2019  Drug Target Review

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Medical Review Board

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johns hopkins internal medicine :: Article Creator Thyrotoxicosis Linked To Risk For Incident Cognitive Disorder For older adults, exposure to a low thyrotropin (TSH) level from either endogenous or exogenous thyrotoxicosis is associated with an increased risk for incident cognitive disorder, according to a study recently published in JAMA Internal Medicine. Roy Adams, Ph.D., from the Johns Hopkins University School of Medicine in Baltimore, and colleagues conducted a cohort study to examine whether thyrotoxicosis is associated with an increased risk for cognitive disorders. Patients aged 65 years and older with at least two visits to their primary care physicians 30 days apart were eligible; the analysis included 65,931 patients. The exposure variable was low TSH level, characterized based on the clinical context as due to endogenous thyrotoxicosis, exogenous thyrotoxicosis, or unknown cause. The researchers found that the incidence of cogn...
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Cases of hand, foot and mouth disease on the rise among Manitoba kids - Global News

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Cases of hand, foot and mouth disease continue to rise among children in Manitoba and across the country, but an infectious disease specialist says it's not surprising to see the virus spread after two years of pandemic restrictions. "Over the past couple of years, we probably forgot about the routine, regular, circulating viral foes that we see in children — one of which being hand, foot and mouth disease," Dr. Justin Penner told Global News. "We certainly could have predicted this — it's not unheard of after two years of a pandemic, when people aren't mixing or aren't in school or daycare." Penner said the disease typically causes non-specific symptoms — fever, cough, some belly symptoms — as well as its namesake fluid-filled blisters on hands and feet and inside the mouth. Read more: Province takes more steps to combat chronic wasting disease "Most cases of hand, foot and mouth disease are self-limited —...
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