Neglected Tropical Diseases

Unlike traditional compressed gas cylinders (tanks filled with oxygen), oxygen concentrators provide a safe source of oxygen-enriched air using room air, which is a mixture of 21% oxygen and 78% nitrogen. An oxygen concentrator draws room air into a cylinder that filters dust, bacteria and other air particles and absorbs nitrogen, which results in concentrated oxygen (90% or higher). There are two types of oxygen concentrators: portable and stationary. Portable models typically use pulse mode delivery in which oxygen is delivered when the user begins to take a breath. Meanwhile, stationary models feature a continuous flow of oxygen. Inogen currently offers three portable oxygen concentrator products—the Inogen One G3, G4 and G5—and one stationary model called Inogen at Home. Below is a summary of their key features. Customization Options and Special Features Splurge on the double battery for the Inogen One models if you want more flexibility with your time away from home. A d...

Overview WHO plays a major role in the cycle of supply chain management for donated and/or procured health products for neglected tropical diseases (NTDs) amenable to preventive chemotherapy and individual case management. This first edition describes the standard operating procedures for health products for NTDs amenable to preventive chemotherapy and the medicines donated to treat them. These include albendazole for lymphatic filariasis and soil-transmitted helminthiases; azithromycin for trachoma and yaws; diethylcarbamazine citrate for lymphatic filariasis; ivermectin for onchocerciasis and lymphatic filariasis; mebendazole for soil-transmitted helminthiases; praziquantel for schistosomiasis; and triclabendazole for foodborne trematodiases. Standard operating procedures for diseases amenable to case management will be covered in subsequent editions, including the application process for requesting medicines (Chapter 1). In the meantime, the procedures described in the ...

Developing a rash under any circumstance can be concerning and a little annoying. But suddenly getting a rash with painful sores is understandably alarming. While plenty of health conditions can cause a rash, there's one in particular that tends to circulate more during the warmer months: hand, foot, and mouth disease. Not familiar with hand, foot, and mouth disease? It's not a comfortable illness, but it's more common than most people realize, says William Schaffner, M.D., an infectious disease specialist at Vanderbilt University School of Medicine. Here's what you need to know. What is hand, foot, and mouth disease? Hand, foot, and mouth disease is a condition that's caused by viruses in the enterovirus family, according to the Centers for Disease Control and Prevention (CDC). Those include coxsackievirus A16—the most common cause of hand, foot, and mouth disease in the U.S.—coxsackievirus A6 , and enterovirus 71 . Hand, foot, and mouth disease spreads through an ...

Bobby Osteen contracted a serious bacterial infection near Galveston, Texas, seven years ago. His wife, Loretta, called 911 when his leg started turning black. Seven years later, Osteen has largely recovered but is still weak, he said. Loading Something is loading. Bobby and Loretta Osteen loved the ocean — t...

There are numerous features to consider when choosing a portable oxygen concentrator, but there are a few particularly important details to think about when browsing your options. Oxygen Delivery Modes While stationary oxygen concentrators deliver a continuous flow of oxygen, portable devices can either provide a continuous flow or a pulse mode, explains Bacheler. Pulse mode POCs can only be used by those using nasal cannulas who have enough breathing power to trigger the device to deliver a pulse of oxygen. People with tracheostomies (a surgical opening in the neck into the trachea) or very poor breathing ability need a continuous flow POC. Some POCs feature both pulse dose and continuous flow settings. It's also important to consider the amount of oxygen needed, says Bacheler. Pulse mode POCs can typically deliver 1 to 6 liters of oxygen per minute, though some small ones are limited to 3 liters per minute. Continuous flow POCs can only provide 1 to 3 liters of oxygen per m...

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Dr. William Schaffner Vanderbilt University Medical Center epidemiologist Dr. William Schaffner does not see monkeypox becoming a threat to the general population.  The Metro Pu...

The rash can vary in severity from minimal painless lesions to multiple painful lesions. Also, some people have the lesions only on one body part while others on multiple body parts. By Connie Colbert GCU Director of Health Services What types of summer illness should you be looking out for? One of them is hand, foot and mouth disease, otherwise known as Coxsackie virus. It is contagious and can spread like wildfire through day cares or families. Connie Colbert It is a common illness that causes sores in or on the mouth, on hands and feet, and sometimes on buttocks and legs. The sores may be painful and make the skin itchy. The illness usually doesn't last more than a week. It is common in children but also can occur in adults. It can occur at any time of year but is most common in the summer and fall. What are the symptoms? Many symptoms are related to hand, foot and mouth disease: A red rash on the palms, without i...

Waiting to refill medical oxygen cylinders for Covid-19 patients at a private refill centre in New Delhi. | Prakash Singh / AFP In a stunning reply to a question in Parliament last July, the Union government reported that it had no information about any deaths anywhere in the country because of the shortage of oxygen. Uttar Pradesh's bellicose saffron-robed Chief Minister Adityanath went so far as to threaten to seize the property of anyone who alleged oxygen shortages, claiming that there was no shortage anywhere. This, at a time when in every corner of the country, oxygen became incalculably more precious than gold. People begged every hospital, pleaded with everyone they knew, harvested any influence they could muster, for oxygen, and too many watched their loved ones choke to death. The BBC fittingly described this as "a nightmare on repeat, waiting for the terrifying moment w...

Kurt Erickson JEFFERSON CITY — Those vittles served up by Robbie Montgomery of Sweetie Pie's restaurant fame may one day be infused with medical-grade marijuana ingredients. But for now, the former background singer for Ike and Tina Turner, who starred in the reality show "Welcome to Sweetie Pie's," remains in legal limbo after the state of Missouri rejected her startup company's application for a cannabis license. According to court filings in Cole County, Grotonics' appeal of its failed bid for a license is under judicial review after an administrative hearing judge ruled the company had failed to provide all the documents needed for its original application to be considered by the Missouri Department of Health and Senior Services. The dispute centers on Grotonics' alleged failure to supply a specific business certifi...

Your child is cranky, running a fever and developing a rash. Once they start refusing to eat, you contact your pediatrician's office — only to learn that this lack of appetite is due to mouth sores from a common but highly infectious childhood illness, hand, foot and mouth disease.  Advertising Policy Cleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. Policy "Like most viruses, it's fairly contagious," says pediatrician Dana Schmidt, MD. "So in a daycare or school setting, it can spread very quickly." Caused by a strain of the coxsackievirus, hand, foot and mouth disease is best known for the blister-like rash it causes on the hands, feet and mouth. However, this rash can appear all over the body. When someone only has blisters in their mouth, but not...

Pitted keratolysis is a bacterial infection of the skin that affects the soles of the feet or the palms of the hands. People with physical jobs that require them to wear enclosed footwear for extended periods, such as those working as farmers or soldiers, may be more likely to develop the infection because bacteria thrive in dark, moist conditions. In this article, learn more about pitted keratolysis, including its causes, symptoms, and treatment. Share on Pinterest Pitted keratolysis can affect both the feet and hands. Image credit: Evan Saap, 2016 Pitted keratolysis is a bacterial infection of the skin. It can affect the palms of the hands and, more commonly, the soles of the feet, particularly the weight-bearing areas. This infection causes small depressions, or pits, in the top layer of the skin. It can also lead to a bad smell. Pitted keratolysis usually affects people who wear enclosed warm footwear for long periods, including soldiers, sailors, and athletes. It also tends to be ...