Medical Review Board
johns hopkins internal medicine :: Article Creator Thyrotoxicosis Linked To Risk For Incident Cognitive Disorder For older adults, exposure to a low thyrotropin (TSH) level from either endogenous or exogenous thyrotoxicosis is associated with an increased risk for incident cognitive disorder, according to a study recently published in JAMA Internal Medicine. Roy Adams, Ph.D., from the Johns Hopkins University School of Medicine in Baltimore, and colleagues conducted a cohort study to examine whether thyrotoxicosis is associated with an increased risk for cognitive disorders. Patients aged 65 years and older with at least two visits to their primary care physicians 30 days apart were eligible; the analysis included 65,931 patients. The exposure variable was low TSH level, characterized based on the clinical context as due to endogenous thyrotoxicosis, exogenous thyrotoxicosis, or unknown cause. The researchers found that the incidence of cogn...
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