Ukraine One-Year Report - Direct Relief

INTRODUCTION


Russia's invasion of Ukraine on Feb. 24, 2022, unleashed a level of suffering upon the Ukrainian people that few thought would ever be seen again in Europe. Eight million people fled Ukraine, and an estimated 5 million more were internally displaced. One year later, the humanitarian crisis and human tragedy deepen as ongoing Russian attacks on civilian electricity infrastructure, homes, and health facilities continue to kill and injure people and cause widespread, enormous psychological trauma.

The onset of war fundamentally altered the status quo in Ukrainian society, creating an immediate gap in essential health services on which Direct Relief focuses. The need for health services spiked at the same moment the capacity to provide services was diminished as hospitals and other health facilities were targeted, millions of people fled their homes, and available resources were redirected from health services to defending Ukraine's territory and people.

Direct Relief responded immediately and has continued an extensive, high-tempo, high-volume operation over the past 12 months. The organization's assistance to Ukraine detailed in this report has been the largest response in its 75-year history – all with private resources, made possible by the extraordinary participation of individuals, organizations, and businesses globally.

People from more than 83 countries – including Russia and Belarus – and all 50 U.S. states and five U.S. territories have contributed to Direct Relief's humanitarian response in support of the Ukrainian people. Direct Relief understands that donor support channeled to the organization was for the people of Ukraine.

This report was written both for those who have so generously participated in Direct Relief's response and for the Ukrainian people on whose behalf the generosity was extended, to help them understand our activities over the past year and our plans moving forward.

Since Feb. 24, 2022, Direct Relief has delivered more than 2.4 million lbs. – over 1,200 tons – of medicine and medical supplies to Ukraine, averaging a delivery every other day for the past 350 or so days. Each item delivered was requested and approved prior to it being sent.

The medical material provided has included 235 million defined daily doses of prescription medications and therapies for a broad range of common conditions and also specialized care, such as for cancers. Huge quantities of medical supplies ranging from battlefield tourniquets and body bags to prenatal vitamins also have been furnished.

The wholesale value of the products delivered $763 million and reflects the value of prescription medications received by donation in Europe, where prices for certain products are as much as 70% lower than comparable products sold in the United States.

As the first and only U.S. nonprofit to become accredited to distribute prescription drugs in all 50 states that also works internationally, Direct Relief engages closely with the healthcare industry, encouraging companies to contribute the medicine and supplies they manufacture to people who cannot buy them. More than 69 companies have stepped up with contributions of their products that are needed by people in Ukraine.

Direct Relief also has committed $30.8 million in financial support to local healthcare organizations providing care in Ukraine and others in countries, including Poland and Slovakia, that have opened their doors to Ukrainian refugees.

That funding has covered medication costs for more than 266,000 Ukrainian refugees in Poland, provided mental health care for close to 25,000 Ukrainian refugees in Slovakia, and funded rehabilitation programs focused on working with amputees, occupational therapy, speech therapy, and psychosocial support. Direct Relief is also providing funding to support Ukraine's national system for distributing medicine around the country to the people who need it.

Despite unavoidable uncertainty about how future events will unfold, events of the past year have made some of the long-term health consequences very clear. People who have sustained disabling injuries will require lifetime care, including children who have lost limbs and will require new prosthetic devices as they grow up. That's why, among other things, Direct Relief is putting money, as well as material aid, into rehabilitation services, which is a priority for the Ukrainian government and health leaders.

As this tragic moment in history unfolds in Ukraine, Direct Relief will continue to serve the people whose lives have been upended, with deepest thanks to each person and organization that is part of this effort.

Thomas Tighe, Direct Relief President & CEO


PART ONE

THE SITUATION

"Direct Relief was created out of the ashes of WWII by Europeans who fled. It's stunning and sad that humanitarian assistance is needed again in the same neighborhood, but it's consistent with our organization's roots, initial focus, and longstanding mission."

– THOMAS TIGHE, Direct Relief President & CEO

The Russian invasion of Ukraine in February 2022 caused widespread and long-lasting disruptions to the country's health care system while drastically increasing the need for health services across all geographies and demographic groups. As of the end of January 2023, over 3.6 million people remained internally displaced, and another 8 million remain outside Ukraine as refugees. In areas of Ukraine where Internally Displaced Persons (IDP)s are concentrated, the number of people seeking healthcare has strained local resources, particularly at the primary care level.

Persistent attacks on health, power and water infrastructure have reduced service capacity across the health system. The greatest impacts occurred in areas close to the front lines in the eastern and southern regions. The intensified attacks since the beginning of October 2022 have destroyed or damaged more than half of Ukraine's power infrastructure, leaving millions of people without a steady supply of power and limited access to water or heat. To battle cold weather, generators and fuel tanks are in high demand. Medical facilities are no exception. Power remains a challenge for the maintenance of the existing services – the medical equipment requires an uninterrupted power supply to operate and to ensure it remains calibrated and functional.

Likewise, reduced access to transportation – given damage, cost, and safety issues – continues to affect every aspect of Ukraine's health system, from patient visits to supply chains. Transportation limitations have reduced physical access to care for many patients and led to persistent stock-outs of needed medications throughout the pharmacy and clinical network. Shortages of medicines exist at the primary health care level, particularly for chronic diseases, including insulin, thyroid gland medication, hormonal therapy, and medicine for heart diseases and chronic obstructive pulmonary disease, as well as a lack of vaccines for tetanus, diphtheria, and other common vaccinations. Access to care remains better in larger towns and cities, but outpatient clinics in smaller settlements and villages are left with almost no equipment and supplies. The situation is worse in frontline areas and recently de-occupied areas, where there are shortages of primary health care providers and almost no functional pharmacies.

Despite the impact of attacks on health infrastructure and other services, health care within Ukraine remains manifestly resilient to shocks. A recent survey by the World Health Organization (WHO) found that 95% of Ukrainians were still receiving primary care services, 90% reported having access to chronic disease care, and 93% were able to access a family doctor either at a clinic or through an expanding network of telemedicine services. The resilience of the health system is a testament at once to the commitment of Ukrainian health professionals and to the strength of international support and collaboration.

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PART TWO

THE APPROACH

"Whenever we are considering an impending donation in the most difficult of conditions and the question is raised internally "Who might be able to handle such a formidable task?" – the answer is always clear. For that reason, we feel proud and humbled to be working so closely with Direct Relief."

– AMALIA ADLER-WAXMAN, SVP, Global Head, ESG and Head of Corporate Affairs of International Markets, Teva Pharmaceuticals

Direct Relief is prioritizing the following strategic areas in its response to the humanitarian crisis in Ukraine:

  • Increase access to health services, including primary health care, prevention and treatment of non-communicable diseases, emergency medical services, and specialized care
  • Ensure delivery of medicines and medical supplies to Ukraine
  • Develop and strengthen rehabilitation services for people wounded by war
  • Increase access to mental health and psychosocial support services
  • Increase access to medical supplies and services for Ukrainian refugees
76 tons of medical aid are loaded into a 777 charter plane at FedEx's distribution center in Memphis, Tennessee, on March 26, 2022, bound for Ukraine. (Lara Cooper/Direct Relief)

In its Ukraine response, Direct Relief continues offering two types of support: medicine and supplies to address disruptions in the medical supply chain, and financial assistance to increase access to health services, improve the supply of medications, and improve the health and well-being of the population.

Direct Relief has built within Ukraine an extensive and constantly expanding network of medical provider partners that include the Ministry of Health, the World Health Organization, regional health departments, public hospitals and clinics, select private hospitals providing services without charge, and local humanitarian foundations and associations.

The Kharkiv Renovation Fund delivering Direct Relief-provided medicines to healthcare providers on December 6, 2022. (Courtesy photo)

Since February 2022, Direct Relief has donated 8.3 million units (e.g., bottles, vials, pre-filled syringes) of prescription medications. Direct Relief also provided millions of units of non-pharmaceutical products such as pen needles, oxygen concentrators, generators, ambulances, medical consumables, and other health care technology.

Letter from The Ukrainian Ministry of Health

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PART THREE

BROADENING Access to health services

"This was nothing about business. We didn't think to help or not; it was so natural. It was a natural consequence of so many people needing help."

– ZBIGNIEW MOLENDA, Founder and VP of Pelion S.A., Poland's largest healthcare sector business

Direct Relief is engaged in several different lines of activity to bolster primary health care in Ukraine. In areas where rural geography and the impact of war have curtailed access, support for mobile health care units will be expanding capacity for early diagnosis, treatment, and prevention of disease. Where health care facilities have seen reduced ability to provide services due to loss of power, the installation of generators and fuel tanks ensures continuous electricity. At the same time, access to medicines is being ensured through a vetted network of non-governmental partners capable of providing regular distribution to primary health facilities and community pharmacies.

In many cases, primary health care can be an excellent place to provide rehabilitation services for those injured by war. Direct Relief is assessing the possibility that an expanded landscape of rehabilitation services can be developed through primary care networks. Likewise, primary care services are linked in Ukraine to the provision of emergency care. Direct Relief is continuing to support emergency services through provision of funding, ambulances, medicines, and supplies.

Issue Spotlight

Diabetes Care for Ukraine
Diabetes Care for Ukraine
Cancer Care for Ukraine
Cancer Care for Ukraine

Primary, Emergency, and Specialized Care Grants

  • Dobrobut Hospital – $2 million
  • Society of Critical Care Medicine – $1.5 million
  • International Confederation of Midwives – $583,000
  • Crown Agents – $500,000
  • Razom for Ukraine – $250,000 for generators and $180,000 for specialized services
  • UA Brokers without Borders – $300,000
  • Ukrainian Diabetes Federation – $150,000
  • Dobrze Urodzeni (Well Born) – $140,000

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PART FOUR

Supplying Medical Material

"We are grateful to be able to use our global network to offer logistics support for organizations like Direct Relief who have long been committed to sourcing and delivering critical supplies in times of crisis. This situation impacts many, including our own Ukrainian team members, and we remain committed to helping during this devastating time."

– KAREN REDDINGTON, Regional President of Europe, FedEx Express

When the war began, Direct Relief had existing relationships with Ukrainian health providers and the Ukrainian Ministry of Health, but it quickly established a far more robust pipeline working closely with European pharmaceutical companies, warehouses, and logistics companies. Direct Relief has increased its agility and flexibility while deepening its relationships and capacity in Europe.

Supporting the Humanitarian Medical Supply Chain

A field hospital was equipped with 50 beds that were handed over to the military. (Photos courtesy of Charity Fund TAPS)

In a country with a government-led healthcare system, Ukraine's Ministry of Health has played a central role in the medical supply chain, both pre-war and during the war. As humanitarian donations of medical supplies poured into Ukraine from around the world, the capacity of the MoH to handle the flow was strained. Direct Relief stepped in to shore up Ukraine's medical supply chain, ensuring that humanitarian medical supplies reached the people that needed them most.

IV fluids from Direct Relief arrive in central Ukraine to support local hospitals in 2022. (Photo courtesy of Charity Fund Modern Village and Town)

For the first few months of the war, the MoH estimated operations costs related to the receipt, handling, and distribution of humanitarian aid at up to $750,000 per month. Currently, with the volume and frequency of donations significantly decreased, the MoH has estimated the added cost of warehousing, handling, and distributing humanitarian medical supplies at $200,000 per month.

Direct Relief has approved a grant of $2 million to the MoH to cover these humanitarian logistics costs for 10 months through the end of 2023.

A surgical X-ray transparent electro -hydraulic table was purchased using Direct Relief-provided funds. This table is the only one in the area, allowing state-of-the-art arterial implantations to be conducted, saving lives and limbs. During the first week, 100 operations were performed. (Courtesy of Charity Fund TAPS)

Direct Relief also provided seven organizations with operational grants to offset the expenses for the receipt and distribution of donated products:

  • Charity Fund Modern Village and Town – $610,000
  • HromadaHub – $220,000
  • Fondation Humanitaire Internationale AICM Ukraine – $250,000
  • Charity Fund "TAPS" – $220,000
  • Charitable Fund Humanitarian Hub Zhytomyr – $210,000
  • Kharkiv Renovation Fund – $150,000
  • Yevgen Pyvovarov's Charity Fund – $90,000

Deploying from Europe

While Direct Relief's Santa Barbara, California,warehouse remains its global distribution hub, the outbreak of war drove Direct Relief to establish a very strong medical supply chain within Europe. More than 40% of pallets of product delivered to Ukraine over the past year have been fulfilled within Europe. Direct Relief has more than doubled the number of healthcare companies donating medicine to the organization from within Europe.

Odesa City Hospital receives a shipment of emergency medical supplies on Oct. 11, 2022. (Photo courtesy of Odesa City Hospital)
First responders in Ukraine deploy with a Direct Relief emergency medic pack. (Courtesy photo)

Direct Relief achieved this significant increase in part by establishing exceptional pharmaceutical warehousing capacity in the Netherlands – fully licensed, professionally staffed, with space for thousands of pallets, and experience in complex humanitarian product imports, exports, and customs clearance. Direct Relief has also arranged large medicine donations drop-shipped directly from donor manufacturer facilities within Ukraine and elsewhere in Europe to its Ukrainian partner organizations.

Cold-Chain Requirements

Many of the most important pharmaceutical products needed in Ukraine – such as insulins, cancer therapies, antibiotics, and immunotherapies – require cold-chain logistics (maintaining temperatures between 2° C and 8° C from factory to patient). Direct Relief has developed a very robust capacity for global cold-chain medicine delivery, using modern software to validate shipping lanes and properly pack the shipments, as well as extensively monitoring temperatures in real-time during the delivery process.

Children with diabetes who have been displaced since Russia's invasion of Ukraine gather at an event organized by the Ukrainian Diabetes Federation Kharkiv region branch. (Courtesy photo)

Direct Relief has been able to deliver over 2.1 million units (vials/cartridges/prefilled syringes) of various types of insulin to its many partner organizations in Ukraine that treat diabetic patients, as well as over 320,000 additional units of cold-chain medicines to treat cancer, infections, immune conditions, blood disorders, and other serious conditions. Included in these figures were shipments to the WHO of donated insulin. Direct Relief also provided 40-foot refrigeration containers to help Ukraine address cold-chain storage capacity issues at key facilities such as the Ukrainian National Cancer Institute in Kyiv.

Generic Industry Provides Vital Essential Medicines

With important coordination and support from the Association of Accessible Medicines (AAM), Medicines for Europe, and the International Generic and Biomedical Association (IGBA), Direct Relief worked closely with its generic pharmaceutical company donors to provide over 130 million defined daily doses of generic medicines to the impacted population of Ukraine.

The companies providing these prescription medicines, which fulfilled them to Direct Relief from both Europe and the United States, include Accord Healthcare, Ajanta Pharma, Alvogen, Apotex, Baxter, Edenbridge, Hikma, ICU Medical, Meitheal Pharmaceuticals, Perrigo, Teva, and Viatris. Their products have been vital to the success of Direct Relief's humanitarian response in Ukraine and provided over 2.5 million units (bottles or vials) with a wholesale value exceeding $170 million. The medicines address therapeutic areas including infections, diabetes, cardiovascular disease, respiratory illness, mental health conditions, ulcers, pain, cancer, and other serious conditions.

Amalia Adler-Waxman, SVP and global head of ESG at Teva, said, "Whenever we are considering an impending donation in the most difficult of conditions and the question is raised internally, 'Who might be able to handle such a formidable task?' The answer is always clear. For that reason, we feel proud and humbled to be working so closely with Direct Relief and look forward to many more years of collaboration and support."

Support from Pharmaceutical and Medical Supply Companies

Sixty-nine global healthcare companies have thus far donated medicine and medical supplies to Direct Relief for its humanitarian response in Ukraine, with a wholesale value of over $763 million USD. The companies that provided the donations include:

3M

Abbott

AbbVie

Accord Healthcare

Ajanta Pharma USA

Alvogen

AmerisourceBergen

Amgen

Apotex

AstraZeneca

Baxter Europe

Baxter International

Bayer AG

Bayer USA

BD

BD Europe

Belmora

Biogen

Boehringer Ingelheim

Cal OES

Carlsbad Technology

Covidien

CVS

DeVilbiss Healthcare GmBH

Dragerwerk AG

Drive Medical GmBH

Edenbridge Pharmaceuticals

Eli Lilly & Company

Encube Ethicals

Ethicon

Genentech

Grifols US

Grifols Worldwide

GSK

GSMS Incorporated

Henry Schein

Hikma Pharmaceuticals

ICU Health

ICU Medical

Inogen

Integra LifeSciences

Janssen Pharmaceuticals

Jazz Pharmaceuticals

J&J Consumer

Kate Farms

Kirk Humanitarian

LifeScan

Liquid IV

McKesson Medical Surgical

Medline Industries

Medtronic

Merck & Co.

Merck KGaA

Meitheal Pharmaceuticals

MSD

Novo Nordisk A/S

Organon

Perrigo Pharmaceuticals

Pfizer

Purdue Pharma

Sanofi

Takeda Pharmaceuticals USA

Teva Pharmaceuticals Europe

Teva Pharmaceuticals USA

Unilever

Unite to Light

Vitaris Europe

Vitaris USA

ViiV Healthcare

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PART FIVE

BOLSTERING REHABILITATIVE SERVICeS

"We are very grateful to Direct Relief for the support of unbroken Ukrainians. With this funding, we will get even more opportunities for the treatment and rehabilitation of our people."

– OLEG SAMCHUK, General Director of the First Lviv Medical Union

According to the United Nations High Commissioner for Human Rights (UNHCR), Ukrainian civilians have suffered nearly 12,000 injuries since the start of the war, and Ukrainian soldiers many more. Many of these individuals require significant medical interventions to repair trauma and physically rehabilitate. Supporting rehabilitation and recovery from war injuries, both physical and psychological, has been a central tenet of Direct Relief's financial support strategy in Ukraine since the war's start.

At Saint Nicholas Pediatric Hospital in Lviv, Ukraine, Mr. Artem (34 years old) plays with Kira (8 months) in the area of Traumatology. Kira was wounded and has shrapnel in her body from when the car in which she and her mother where traveling in was attacked. Her mother was also wounded and lost a finger while escaping and caring for Kira and another child. (Courtesy photo)

To strengthen rehabilitation services in Ukraine, Direct Relief is prioritizing the following areas:

  • Strengthening in-patient rehabilitation departments in hospitals identified by the Ukrainian Ministry of He...

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